Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50095480'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50095480 (CHEMBL3590484 | US10329294, Example 5) Show SMILES Cn1cc(NC(=O)c2cnn3ccc(NC4CCCCC4)nc23)c(n1)C(F)(F)F Show InChI InChI=1S/C18H20F3N7O/c1-27-10-13(15(26-27)18(19,20)21)24-17(29)12-9-22-28-8-7-14(25-16(12)28)23-11-5-3-2-4-6-11/h7-11H,2-6H2,1H3,(H,23,25)(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of human IRAK4 assessed as phosphorylation of fluorescent peptide substrate after 30 mins by fluorescent polarization reader				ACS Med Chem Lett 6: 683-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00107 BindingDB Entry DOI: 10.7270/Q2QF8VNH
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50095480 (CHEMBL3590484 | US10329294, Example 5) Show SMILES Cn1cc(NC(=O)c2cnn3ccc(NC4CCCCC4)nc23)c(n1)C(F)(F)F Show InChI InChI=1S/C18H20F3N7O/c1-27-10-13(15(26-27)18(19,20)21)24-17(29)12-9-22-28-8-7-14(25-16(12)28)23-11-5-3-2-4-6-11/h7-11H,2-6H2,1H3,(H,23,25)(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd					Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...				Bioorg Med Chem 17: 6590-605 (2009) BindingDB Entry DOI: 10.7270/Q2V40XJ3
					More data for this Ligand-Target Pair