BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-2 receptor subunit alpha' and Ligand = 'BDBM50148003'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-2 receptor subunit alpha


(Mus musculus)		BDBM50148003
PNG
(4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Show SMILES [#6]-[#8]-[#6](=O)-c1ccc(-[#6]-[#8]-c2ccc(-c3cc(-[#6]-4-[#6]-[#6]-[#7](-[#6]-[#6]-4)-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])\[#7]=[#6](/[#7])-[#7])n(-[#6])n3)c(Cl)c2Cl)cc1
Show InChI InChI=1S/C33H41Cl2N7O5/c1-19(2)15-25(39-33(36)37)31(44)38-17-28(43)42-13-11-21(12-14-42)26-16-24(40-41(26)3)23-9-10-27(30(35)29(23)34)47-18-20-5-7-22(8-6-20)32(45)46-4/h5-10,16,19,21,25H,11-15,17-18H2,1-4H3,(H,38,44)(H4,36,37,39)/t25-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay

J Med Chem 47: 3111-30 (2004)


Article DOI: 10.1021/jm049967u
BindingDB Entry DOI: 10.7270/Q2TQ6280
More data for this
Ligand-Target Pair