BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-2 receptor subunit alpha' and Ligand = 'BDBM50229786'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Interleukin-2 receptor subunit alpha (Mus musculus)	BDBM50229786 (5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-P...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Interleukin-2 receptor subunit alpha (Mus musculus)	BDBM50229786 (5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-P...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Effective concentration required against phosphorylation of Mammary gland factor/STAT5				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair