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Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-5' and Ligand = 'BDBM50277124'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-5


(Mus musculus)		BDBM50277124
PNG
(CHEMBL4168121)
Show SMILES [O-][N+](=O)c1ccc(COc2coc3cccc(CC4CCCCC4)c3c2=O)cc1
Show InChI InChI=1S/C23H23NO5/c25-23-21(28-14-17-9-11-19(12-10-17)24(26)27)15-29-20-8-4-7-18(22(20)23)13-16-5-2-1-3-6-16/h4,7-12,15-16H,1-3,5-6,13-14H2
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MMDB

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Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair