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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-5 receptor subunit alpha' and Ligand = 'BDBM50517051'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517051
PNG
(CHEMBL4567563)
Show SMILES COc1ccc(CNCc2nc3c(OCC4CCCCC4)cccc3[nH]2)cc1
Show InChI InChI=1S/C23H29N3O2/c1-27-19-12-10-17(11-13-19)14-24-15-22-25-20-8-5-9-21(23(20)26-22)28-16-18-6-3-2-4-7-18/h5,8-13,18,24H,2-4,6-7,14-16H2,1H3,(H,25,26)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair