Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Interleukin-6' and Ligand = 'BDBM419258'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM419258 (US10457681, Compound Ia-06 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC6CCC6)cc5Sc4c3)c2n1 Show InChI InChI=1S/C28H33N7O2S/c1-3-4-12-37-27-32-25(29)24-26(33-27)35(28(36)31-24)16-18-9-11-21-23(14-18)38-22-13-17(8-10-20(22)34(21)2)15-30-19-6-5-7-19/h8-11,13-14,19,30H,3-7,12,15-16H2,1-2H3,(H,31,36)(H2,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	88.7	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...				US Patent US10487084 (2019) BindingDB Entry DOI: 10.7270/Q2P55QX7
					More data for this Ligand-Target Pair
Interleukin-6 (Homo sapiens (Human))	BDBM419258 (US10457681, Compound Ia-06 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC6CCC6)cc5Sc4c3)c2n1 Show InChI InChI=1S/C28H33N7O2S/c1-3-4-12-37-27-32-25(29)24-26(33-27)35(28(36)31-24)16-18-9-11-21-23(14-18)38-22-13-17(8-10-20(22)34(21)2)15-30-19-6-5-7-19/h8-11,13-14,19,30H,3-7,12,15-16H2,1-2H3,(H,31,36)(H2,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Companay US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10981914 (2021) BindingDB Entry DOI: 10.7270/Q23X89RG
					More data for this Ligand-Target Pair
Interleukin-6 (Homo sapiens (Human))	BDBM419258 (US10457681, Compound Ia-06 | US10487084, Compound ...) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC6CCC6)cc5Sc4c3)c2n1 Show InChI InChI=1S/C28H33N7O2S/c1-3-4-12-37-27-32-25(29)24-26(33-27)35(28(36)31-24)16-18-9-11-21-23(14-18)38-22-13-17(8-10-20(22)34(21)2)15-30-19-6-5-7-19/h8-11,13-14,19,30H,3-7,12,15-16H2,1-2H3,(H,31,36)(H2,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Bristol_Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10457681 (2019) BindingDB Entry DOI: 10.7270/Q2N87D54
					More data for this Ligand-Target Pair