Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-6' and Ligand = 'BDBM423486'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM423486 (US10508115, Compound Ib-05) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5COC5)cc4)nc3)c2n1 Show InChI InChI=1S/C25H29N7O4/c1-2-3-10-35-24-30-22(26)21-23(31-24)32(25(33)29-21)13-17-6-9-20(28-12-17)36-19-7-4-16(5-8-19)11-27-18-14-34-15-18/h4-9,12,18,27H,2-3,10-11,13-15H2,1H3,(H,29,33)(H2,26,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.57	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10508115 (2019) BindingDB Entry DOI: 10.7270/Q2K35X2W
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