Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-6' and Ligand = 'BDBM423500'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM423500 (US10508115, Compound Ic-02) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4cccc(CNC5CCC5)n4)cc3)c2n1 Show InChI InChI=1S/C26H31N7O3/c1-2-3-14-35-25-31-23(27)22-24(32-25)33(26(34)30-22)16-17-10-12-20(13-11-17)36-21-9-5-8-19(29-21)15-28-18-6-4-7-18/h5,8-13,18,28H,2-4,6-7,14-16H2,1H3,(H,30,34)(H2,27,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16.1	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10508115 (2019) BindingDB Entry DOI: 10.7270/Q2K35X2W
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