Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-6' and Ligand = 'BDBM423519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM423519 (US10508115, Compound Ie-05) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNCCOC)cc4)c(F)c3)c2n1 Show InChI InChI=1S/C26H31FN6O4/c1-3-4-12-36-25-31-23(28)22-24(32-25)33(26(34)30-22)16-18-7-10-21(20(27)14-18)37-19-8-5-17(6-9-19)15-29-11-13-35-2/h5-10,14,29H,3-4,11-13,15-16H2,1-2H3,(H,30,34)(H2,28,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...				US Patent US10508115 (2019) BindingDB Entry DOI: 10.7270/Q2K35X2W
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