BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interstitial collagenase' and Ligand = 'BDBM50013121'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interstitial collagenase


(Homo sapiens (Human))		BDBM50013121
PNG
(CHEMBL2372451)
Show SMILES CCOP(O)(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)NCC(O)=O |r|
Show InChI InChI=1S/C26H47N10O14P/c1-5-14(3)21(35-51(48,49)50-6-2)25(45)31-15(4)22(42)29-12-18(37)32-17(9-10-19(38)39)24(44)33-16(23(43)30-13-20(40)41)8-7-11-28-26(27)34-36(46)47/h14-17,21H,5-13H2,1-4H3,(H,29,42)(H,30,43)(H,31,45)(H,32,37)(H,33,44)(H,38,39)(H,40,41)(H3,27,28,34)(H2,35,48,49)/t14-,15-,16-,17-,21-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 2.70E+5n/an/an/an/an/an/a7.5n/a



University of Kentucky

Curated by ChEMBL


Assay Description
Assayed against human skin fibroblast Collagenase using the spectrophotometric assay with the thiol ester substrate at pH 6.5.

J Med Chem 33: 263-73 (1990)


BindingDB Entry DOI: 10.7270/Q2J9670V
More data for this
Ligand-Target Pair