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Found 1 hit Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM222260'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intestinal-type alkaline phosphatase


(Bos taurus (Cattle))		BDBM222260
PNG
((Z)-4-(2-((E)-4-(3-methoxyphenyl)-1-morpholino-2-o...)
Show SMILES COc1cccc(\C=C\C(=O)C(=N\Nc2ccc(cc2)S(N)(=O)=O)\N2CCOCC2)c1
Show InChI InChI=1S/C21H24N4O5S/c1-29-18-4-2-3-16(15-18)5-10-20(26)21(25-11-13-30-14-12-25)24-23-17-6-8-19(9-7-17)31(22,27)28/h2-10,15,23H,11-14H2,1H3,(H2,22,27,28)/b10-5+,24-21-
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 990n/an/an/an/a9.837



COMSATS Institute of Information Technology



Assay Description
Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat...

Bioorg Chem 70: 229-236 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.003
BindingDB Entry DOI: 10.7270/Q2K07334
More data for this
Ligand-Target Pair