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Found 1 hit Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM222267'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intestinal-type alkaline phosphatase


(Bos taurus (Cattle))		BDBM222267
PNG
((Z)-4-(2-((E)-1-morpholino-4-(3-Nitrophenyl)-2-oxo...)
Show SMILES NS(=O)(=O)c1ccc(N\N=C(/N2CCOCC2)C(=O)\C=C\c2cccc(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C20H21N5O6S/c21-32(29,30)18-7-5-16(6-8-18)22-23-20(24-10-12-31-13-11-24)19(26)9-4-15-2-1-3-17(14-15)25(27)28/h1-9,14,22H,10-13H2,(H2,21,29,30)/b9-4+,23-20-
UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 740n/an/an/an/a9.837



COMSATS Institute of Information Technology



Assay Description
Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat...

Bioorg Chem 70: 229-236 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.003
BindingDB Entry DOI: 10.7270/Q2K07334
More data for this
Ligand-Target Pair