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Found 1 hit Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM50464731'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intestinal-type alkaline phosphatase


(Homo sapiens (Human))		BDBM50464731
PNG
(CHEMBL4295150)
Show SMILES CCOc1ccc(Nc2nn3c(nc(cc3=O)C(F)(F)F)s2)cc1
Show InChI InChI=1S/C14H11F3N4O2S/c1-2-23-9-5-3-8(4-6-9)18-12-20-21-11(22)7-10(14(15,16)17)19-13(21)24-12/h3-7H,2H2,1H3,(H,18,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.02E+3n/an/an/an/an/an/a



Universit£t Rostock

Curated by ChEMBL


Assay Description
Inhibition of human IAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by ...

Eur J Med Chem 144: 116-127 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.068
BindingDB Entry DOI: 10.7270/Q2W66PDP
More data for this
Ligand-Target Pair