Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of East Anglia Curated by ChEMBL | Assay Description Inhibition of Candida albicans isocitrate lyase after 30 mins | Bioorg Med Chem Lett 21: 7142-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.072 BindingDB Entry DOI: 10.7270/Q28G8M3R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of Candida albicans isocitrate lyase | J Nat Prod 74: 1805-11 (2011) Article DOI: 10.1021/np200492k BindingDB Entry DOI: 10.7270/Q2C53M7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of recombinant Candida albicans ATCC 10231 ICL using phenylhydrazine and isocitrate as substrate assessed as formation of glyoxylate pheny... | Bioorg Med Chem Lett 23: 4099-101 (2013) Article DOI: 10.1016/j.bmcl.2013.05.051 BindingDB Entry DOI: 10.7270/Q2Z3212D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of Candida albicans recombinant ICL assessed as formation of glyoxylate phenylhydrazone by spectrophotometry | Bioorg Med Chem 20: 4082-7 (2012) Article DOI: 10.1016/j.bmc.2012.05.002 BindingDB Entry DOI: 10.7270/Q29S1S3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of candida albicans isocitrate lyase | Bioorg Med Chem Lett 18: 5377-80 (2008) Article DOI: 10.1016/j.bmcl.2008.09.059 BindingDB Entry DOI: 10.7270/Q2BV7HKT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of Candida albicans ATCC 10231 isocitrate lyase | Bioorg Med Chem Lett 20: 6644-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.015 BindingDB Entry DOI: 10.7270/Q22V2GBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Mycobacterium tuberculosis) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Mycobacterium tuberculosis recombinant isocitrate lyase expressed in Escherichia coli BL21 (DE3) using isocitrate as substrate after 10... | Citation and Details Article DOI: 10.1007/s00044-013-0845-4 BindingDB Entry DOI: 10.7270/Q27H1M17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Inhibition of Candida albicans isocitrate lyase | Bioorg Med Chem Lett 19: 1051-3 (2009) Article DOI: 10.1016/j.bmcl.2009.01.017 BindingDB Entry DOI: 10.7270/Q2CC11MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Inhibition of Candida albicans isocitrate lyase | Bioorg Med Chem Lett 20: 6882-5 (2010) Article DOI: 10.1016/j.bmcl.2010.10.029 BindingDB Entry DOI: 10.7270/Q2M61KGZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Candida albicans) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Inhibition of Candida albicans ATCC 10231 isocitrate lyase by spectrophotmeric analysis | J Nat Prod 75: 2055-61 (2012) Article DOI: 10.1021/np3005562 BindingDB Entry DOI: 10.7270/Q2416Z76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Magnaporthe oryzae (strain 70-15 / FGSC 8958) (Ric...) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Ocean Research and Development Institute Curated by ChEMBL | Assay Description Inhibition of Magnaporthe grisea Guy 11 isocitrate lyase | Bioorg Med Chem Lett 17: 2483-6 (2007) Article DOI: 10.1016/j.bmcl.2007.02.027 BindingDB Entry DOI: 10.7270/Q2N87BKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isocitrate lyase (Mycobacterium tuberculosis) | BDBM50274515 (3-nitropropanoic acid | 3-nitropropionic acid | Bo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.16E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology and Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis isocitrate lyase | Bioorg Med Chem Lett 21: 5149-54 (2011) Article DOI: 10.1016/j.bmcl.2011.07.062 BindingDB Entry DOI: 10.7270/Q20002GQ | |||||||||||
More data for this Ligand-Target Pair |