Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 2 of Histone lysine demethylase PHF8 (2)' and Ligand = 'BDBM276088'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276088 (1-(2-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccccc1-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-3-1-2-4-14(9)21-7-13(17-8-21)10-5-11-12(6-16-10)19-20-18-11/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair