Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM176782'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM176782 (US9675612, 25 5-Methoxy-6-{[2-(2-phenylethyl)[1,3]...) Show SMILES COc1cc2[nH]c(=O)sc2cc1Nc1ncnc2sc(CCc3ccccc3)nc12 Show InChI InChI=1S/C21H17N5O2S2/c1-28-15-9-14-16(29-21(27)25-14)10-13(15)24-19-18-20(23-11-22-19)30-17(26-18)8-7-12-5-3-2-4-6-12/h2-6,9-11H,7-8H2,1H3,(H,25,27)(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
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