Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM223043'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM223043 (US9320737, IV.2) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=N)=O)nn12 |w:22.24| Show InChI InChI=1S/C19H20N4O4S/c1-25-15-5-3-6-16-13(15)11-17(27-16)14-12-21-18-7-8-19(22-23(14)18)26-9-4-10-28(2,20)24/h3,5-8,11-12,20H,4,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
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