Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM343676'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343676 (2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...) Show SMILES C(COc1ccc2ncc(-c3cc4ccccc4o3)n2n1)NCC1CC1 Show InChI InChI=1S/C20H20N4O2/c1-2-4-17-15(3-1)11-18(26-17)16-13-22-19-7-8-20(23-24(16)19)25-10-9-21-12-14-5-6-14/h1-4,7-8,11,13-14,21H,5-6,9-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343676 (2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...) Show SMILES C(COc1ccc2ncc(-c3cc4ccccc4o3)n2n1)NCC1CC1 Show InChI InChI=1S/C20H20N4O2/c1-2-4-17-15(3-1)11-18(26-17)16-13-22-19-7-8-20(23-24(16)19)25-10-9-21-12-14-5-6-14/h1-4,7-8,11,13-14,21H,5-6,9-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair