Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM343679'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343679 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H20N4O2/c1-13(2)20-9-10-24-19-8-7-18-21-12-15(23(18)22-19)17-11-14-5-3-4-6-16(14)25-17/h3-8,11-13,20H,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343679 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H20N4O2/c1-13(2)20-9-10-24-19-8-7-18-21-12-15(23(18)22-19)17-11-14-5-3-4-6-16(14)25-17/h3-8,11-13,20H,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair