Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D]' and Ligand = 'BDBM420262'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM420262 ((4-[2-Dimethylamino)ethyl]methyl)aminopiperidin-1-...) Show SMILES COc1cn2nccc2cc1Nc1ncnc2sc3C[C@H](CCc3c12)C(=O)N1CCC(CC1)N(C)CCN(C)C |r| Show InChI InChI=1S/C29H38N8O2S/c1-34(2)13-14-35(3)20-8-11-36(12-9-20)29(38)19-5-6-22-25(15-19)40-28-26(22)27(30-18-31-28)33-23-16-21-7-10-32-37(21)17-24(23)39-4/h7,10,16-20H,5-6,8-9,11-15H2,1-4H3,(H,30,31,33)/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...				US Patent US10487092 (2019) BindingDB Entry DOI: 10.7270/Q28W3GPZ
					More data for this Ligand-Target Pair