Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A8)' and Ligand = 'BDBM399954'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A8) (Homo sapiens (Human))	BDBM399954 (US10323042, Example 34 | US10738063, Example 34) Show SMILES CC(C)NC(=O)c1nn2CCCOc2c1-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C16H17ClFN3O2/c1-9(2)19-15(22)14-13(10-4-5-11(17)12(18)8-10)16-21(20-14)6-3-7-23-16/h4-5,8-9H,3,6-7H2,1-2H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
CNR					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				J Med Chem 52: 5990-8 (2009) BindingDB Entry DOI: 10.7270/Q2NP26RH
					More data for this Ligand-Target Pair