Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform APP695 of Amyloid-beta precursor protein [K595N,M596L]' and Ligand = 'BDBM571404'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform APP695 of Amyloid-beta precursor protein [K595N,M596L] (Homo sapiens (Human))	BDBM571404 ((9R)-N-[3-(4-methylimidazol-1-yl)-1-bicyclo[1.1.1]...) Show SMILES Cc1cn(cn1)C12CC(C1)(C2)Nc1nc2[C@H](CCCCn2n1)c1ccc(F)c(F)c1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA					Assay Description Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NF1
					More data for this Ligand-Target Pair