Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform Tau-F of Microtubule-associated protein tau' and Ligand = 'BDBM214726'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform Tau-F of Microtubule-associated protein tau (Homo sapiens (Human))	BDBM214726 (Cyanines, 9) Show SMILES C1CC[n+]2c(\C=C\C=C3/Sc4ccccc4N3CCCC[n+]3c(\C=C\C=C4/Sc5ccccc5N4C1)sc1ccccc31)sc1ccccc21 |c:7,27,t:5,25| Show InChI InChI=1S/C42H38N4S4/c1-5-19-35-31(15-1)43-27-9-10-28-44-32-16-2-6-20-36(32)49-41(44)25-14-26-42-46(34-18-4-8-22-38(34)50-42)30-12-11-29-45-33-17-3-7-21-37(33)48-40(45)24-13-23-39(43)47-35/h1-8,13-26H,9-12,27-30H2/q+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
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