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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Isoform Tau-F of Microtubule-associated protein tau' and Ligand = 'BDBM576626'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoform Tau-F of Microtubule-associated protein tau


(Homo sapiens (Human))
BDBM576626
PNG
(US11472776, Example 15)
Show SMILES O=c1[nH]c(nc2ccsc12)-c1cccnc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.72E+3n/an/an/an/an/an/a


TBA

Assay Description
AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2ZW1Q5K
More data for this
Ligand-Target Pair
Isoform Tau-F of Microtubule-associated protein tau


(Homo sapiens (Human))
BDBM576626
PNG
(US11472776, Example 15)
Show SMILES O=c1[nH]c(nc2ccsc12)-c1cccnc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2ZW1Q5K
More data for this
Ligand-Target Pair