BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM200010'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kallikrein-1


(Homo sapiens (Human))		BDBM200010
PNG
(US9234000, 1)
Show SMILES CCOc1ccc(CC(=O)CNN([C@@H](Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)C(=O)CC)cc1
Show InChI InChI=1S/C31H38N4O4/c1-3-30(37)35(34-22-27(36)18-24-14-16-28(17-15-24)39-4-2)29(19-23-8-6-5-7-9-23)31(38)33-21-26-12-10-25(20-32)11-13-26/h5-17,29,34H,3-4,18-22,32H2,1-2H3,(H,33,38)/t29-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



Kalvista Pharmaceuticals Limited

US Patent


Assay Description
KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...

US Patent US9234000 (2016)


BindingDB Entry DOI: 10.7270/Q2X065W0
More data for this
Ligand-Target Pair