Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM335739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM335739 (US9738641, 4 | [1-(2-Phenyl-thiazol-4-ylmethyl)-1H...) Show SMILES C(Nc1nccc2n(Cc3csc(n3)-c3ccccc3)ccc12)c1cnc2[nH]ccc2c1 Show InChI InChI=1S/C25H20N6S/c1-2-4-18(5-3-1)25-30-20(16-32-25)15-31-11-8-21-22(31)7-10-27-24(21)29-14-17-12-19-6-9-26-23(19)28-13-17/h1-13,16H,14-15H2,(H,26,28)(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9738641 (2017) BindingDB Entry DOI: 10.7270/Q2M047K7
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