Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM335743'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM335743 (1-{4-[4-(4-Aminomethyl-2-methyl-benzylamino)-pyrro...) Show SMILES Cc1cc(CN)ccc1CNc1nccc2n(Cc3ccc(Cn4ccccc4=O)cc3)ccc12 Show InChI InChI=1S/C29H29N5O/c1-21-16-24(17-30)9-10-25(21)18-32-29-26-12-15-33(27(26)11-13-31-29)19-22-5-7-23(8-6-22)20-34-14-3-2-4-28(34)35/h2-16H,17-20,30H2,1H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9738641 (2017) BindingDB Entry DOI: 10.7270/Q2M047K7
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