Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM335744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM335744 ((4-Aminomethyl-benzyl)-[1-(2-phenyl-thiazol-4-ylme...) Show SMILES NCc1ccc(CNc2nccc3n(Cc4csc(n4)-c4ccccc4)ccc23)cc1 Show InChI InChI=1S/C25H23N5S/c26-14-18-6-8-19(9-7-18)15-28-24-22-11-13-30(23(22)10-12-27-24)16-21-17-31-25(29-21)20-4-2-1-3-5-20/h1-13,17H,14-16,26H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9738641 (2017) BindingDB Entry DOI: 10.7270/Q2M047K7
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