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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-14' and Ligand = 'BDBM50522493'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kallikrein-14


(Homo sapiens (Human))		BDBM50522493
PNG
(CHEMBL4530083)
Show SMILES NC(=N)c1ccc(NCc2nc(c[nH]2)-c2ccccc2)cc1OCc1cccnc1
Show InChI InChI=1S/C23H22N6O/c24-23(25)19-9-8-18(11-21(19)30-15-16-5-4-10-26-12-16)27-14-22-28-13-20(29-22)17-6-2-1-3-7-17/h1-13,27H,14-15H2,(H3,24,25)(H,28,29)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of recombinant C-terminal 10His-tagged human KLK14 (Gln19 to Met248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate ...

Bioorg Med Chem Lett 29: 1454-1458 (2019)


Article DOI: 10.1016/j.bmcl.2019.04.022
BindingDB Entry DOI: 10.7270/Q24F1V4V
More data for this
Ligand-Target Pair