Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM222966 (US9315514, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 757 | -34.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Rhodes Technologies US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin... | US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM222966 (US9315514, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | 7.4 | 25 |
Rhodes Technologies US Patent | Assay Description Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f... | US Patent US9315514 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DWC | |||||||||||
More data for this Ligand-Target Pair |