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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50041568'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50041568
PNG
(17-(cyclopropylmethyl)-17'-[2-[(carbobenzyloxy)ami...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C=C8N(CCNC(=O)OCc9ccccc9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |t:31,TLB:54:26:46:29.44.43,24:25:46:29.44.43|
Show InChI InChI=1S/C46H46N4O8/c51-30-10-8-26-18-32-45(54)20-28-29-21-46(55)33-19-27-9-11-31(52)39-35(27)44(46,13-16-50(33)22-24-6-7-24)41(58-39)37(29)48-36(28)40-43(45,34(26)38(30)57-40)12-15-49(32)17-14-47-42(53)56-23-25-4-2-1-3-5-25/h1-5,8-11,18,24,33,40-41,48,51-52,54-55H,6-7,12-17,19-23H2,(H,47,53)/t33-,40+,41+,43+,44+,45-,46-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.360n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligand

J Med Chem 37: 1495-500 (1994)


BindingDB Entry DOI: 10.7270/Q2XP75K7
More data for this
Ligand-Target Pair