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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50059818'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50059818
PNG
(4-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Show SMILES CCCCN(CCCC)C(=O)c1ccc(cc1)[C@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C32H47N3O2/c1-7-10-20-33(21-11-8-2)32(36)28-17-15-27(16-18-28)31(29-13-12-14-30(22-29)37-6)35-24-25(4)34(19-9-3)23-26(35)5/h9,12-18,22,25-26,31H,3,7-8,10-11,19-21,23-24H2,1-2,4-6H3/t25-,26+,31+/m1/s1
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.50E+3n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity for Opioid receptor kappa 1 by the inhibition of binding of [3H]U-69593 in guinea pig brain membranes.

J Med Chem 40: 2936-47 (1997)


Article DOI: 10.1021/jm970106d
BindingDB Entry DOI: 10.7270/Q2G44QZ3
More data for this
Ligand-Target Pair