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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50059823'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50059823
PNG
(4-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Show SMILES COc1cccc(c1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccc(cc1)C(=O)N(C(C)C)C(C)C
Show InChI InChI=1S/C30H43N3O2/c1-9-17-31-19-24(7)32(20-23(31)6)29(27-11-10-12-28(18-27)35-8)25-13-15-26(16-14-25)30(34)33(21(2)3)22(4)5/h9-16,18,21-24,29H,1,17,19-20H2,2-8H3/t23-,24+,29+/m1/s1
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.50E+3n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity for Opioid receptor kappa 1 by the inhibition of binding of [3H]U-69593 in guinea pig brain membranes.

J Med Chem 40: 2936-47 (1997)


Article DOI: 10.1021/jm970106d
BindingDB Entry DOI: 10.7270/Q2G44QZ3
More data for this
Ligand-Target Pair