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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50077083'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50077083
PNG
(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(Cc2ccc3OCOc3c2)CC1)c1ccccc1
Show InChI InChI=1S/C30H35N3O3/c1-3-32(4-2)30(34)26-13-11-25(12-14-26)29(24-8-6-5-7-9-24)33-18-16-31(17-19-33)21-23-10-15-27-28(20-23)36-22-35-27/h5-15,20,29H,3-4,16-19,21-22H2,1-2H3
PDB

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Organon Laboratories Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranes

Bioorg Med Chem Lett 9: 1329-34 (1999)


BindingDB Entry DOI: 10.7270/Q2V40TCM
More data for this
Ligand-Target Pair