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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50088370'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50088370
PNG
(1-{10-[3-(4-Nitro-phenyl)-allyl]-9,10-diaza-tricyc...)
Show SMILES CCC(=O)N1C2CC[C@H]1[C@@H]1CCC2N1C\C=C\c1ccc(cc1)[N+]([O-])=O |TLB:2:4:13:11.10,11:12:4:6.7,10:9:4:6.7,THB:14:13:4.5.8:11.10,14:13:4:6.7,6:5:13:11.10,7:8:13:11.10|
Show InChI InChI=1S/C20H25N3O3/c1-2-20(24)22-18-11-12-19(22)17-10-9-16(18)21(17)13-3-4-14-5-7-15(8-6-14)23(25)26/h3-8,16-19H,2,9-13H2,1H3/b4-3+/t16-,17?,18-,19?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Istituto di Chimica Farmaceutica e Tossicologica

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor kappa 1 was determined in guinea pig homogenate using [3H]-U-69,593 as radioligand

J Med Chem 43: 2115-23 (2000)


BindingDB Entry DOI: 10.7270/Q22N51HT
More data for this
Ligand-Target Pair