Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50108434'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50108434 (3-[2-Oxo-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1,2-...) Show SMILES O=c1c(cccn1C(CN1CCCC1)c1ccccc1)-c1cccc(c1)C#N Show InChI InChI=1S/C24H23N3O/c25-17-19-8-6-11-21(16-19)22-12-7-15-27(24(22)28)23(18-26-13-4-5-14-26)20-9-2-1-3-10-20/h1-3,6-12,15-16,23H,4-5,13-14,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin A				Bioorg Med Chem Lett 12: 197-200 (2001) BindingDB Entry DOI: 10.7270/Q28051XH
					More data for this Ligand-Target Pair