Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50256673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50256673 (CHEMBL4102551) Show SMILES Cl.[H][C@]12CCC[C@](CCN1CCc1ccc(cc1)C(F)(F)F)([C@@H]2O)c1cccc(O)c1 |r,THB:10:9:5.4.3:22| Show InChI InChI=1S/C23H26F3NO2.ClH/c24-23(25,26)17-8-6-16(7-9-17)10-13-27-14-12-22(11-2-5-20(27)21(22)29)18-3-1-4-19(28)15-18;/h1,3-4,6-9,15,20-21,28-29H,2,5,10-14H2;1H/t20-,21-,22-;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Al Curated by ChEMBL					Assay Description Displacement of [3H]U-69,593 from kappa opioid receptor in rat brain after 60 mins by liquid scintillation counting method				Bioorg Med Chem 25: 2406-2422 (2017) Article DOI: 10.1016/j.bmc.2017.02.064 BindingDB Entry DOI: 10.7270/Q2765HS8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50256673 (CHEMBL4102551) Show SMILES Cl.[H][C@]12CCC[C@](CCN1CCc1ccc(cc1)C(F)(F)F)([C@@H]2O)c1cccc(O)c1 |r,THB:10:9:5.4.3:22| Show InChI InChI=1S/C23H26F3NO2.ClH/c24-23(25,26)17-8-6-16(7-9-17)10-13-27-14-12-22(11-2-5-20(27)21(22)29)18-3-1-4-19(28)15-18;/h1,3-4,6-9,15,20-21,28-29H,2,5,10-14H2;1H/t20-,21-,22-;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	761	n/a	n/a	n/a	n/a
Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Al Curated by ChEMBL					Assay Description Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr ...				Bioorg Med Chem 25: 2406-2422 (2017) Article DOI: 10.1016/j.bmc.2017.02.064 BindingDB Entry DOI: 10.7270/Q2765HS8
					More data for this Ligand-Target Pair