BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50297345'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50297345 ((5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...				J Med Chem 52: 5619-25 (2009) Article DOI: 10.1021/jm900577k BindingDB Entry DOI: 10.7270/Q2QN66T6
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair