Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kelch-like ECH-associated protein 1 (Homo sapiens (Human)) | BDBM415702 (US10442759, Compound I-14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00830 BindingDB Entry DOI: 10.7270/Q2NV9PCR | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kelch-like ECH-associated protein 1 (Homo sapiens (Human)) | BDBM415702 (US10442759, Compound I-14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to purified Keap1 Kelch domain (unknown origin) by isothermal titration calorimetry | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112734 BindingDB Entry DOI: 10.7270/Q2FJ2MGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kelch-like ECH-associated protein 1 (Homo sapiens (Human)) | BDBM415702 (US10442759, Compound I-14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to biotinylated-Keap1 Kelch domain (unknown origin) by biolayer interferometry | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112734 BindingDB Entry DOI: 10.7270/Q2FJ2MGN | |||||||||||
More data for this Ligand-Target Pair |