Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50502731'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 (Homo sapiens (Human))	BDBM50502731 (CHEMBL4530659) Show SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1cccnc1-c1cnn(C)c1 |c:9| Show InChI InChI=1S/C19H20N4O2/c1-18(2)12-19(25-4,8-13(9-20)17(18)24)15-6-5-7-21-16(15)14-10-22-23(3)11-14/h5-8,10-11H,12H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of KEAP1 interaction with Nrf2 in human HEK293 cells transfected with ARE-LUC assessed as activation of Nrf2 signaling pathway measured af...				ACS Med Chem Lett 10: 1245-1246 (2019) Article DOI: 10.1021/acsmedchemlett.9b00328 BindingDB Entry DOI: 10.7270/Q2QZ2F72
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