Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50213730 ((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Cancer Research Curated by ChEMBL | Assay Description Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activity | J Med Chem 54: 1576-86 (2011) Article DOI: 10.1021/jm100991m BindingDB Entry DOI: 10.7270/Q2154HC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50213730 ((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Shizuoka Curated by ChEMBL | Assay Description Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assay | Bioorg Med Chem Lett 17: 3921-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.101 BindingDB Entry DOI: 10.7270/Q2542N8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50213730 ((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 262 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Shizuoka Curated by ChEMBL | Assay Description Binding affinity against delta opioid receptor in mouse hot plate test | ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76 | |||||||||||
More data for this Ligand-Target Pair |