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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM50322573'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))
BDBM50322573
PNG
(3-methyl-6-(trifluoromethyl)-9H-carbazole | CHEMBL...)
Show SMILES Cc1ccc2[nH]c3ccc(cc3c2c1)C(F)(F)F
Show InChI InChI=1S/C14H10F3N/c1-8-2-4-12-10(6-8)11-7-9(14(15,16)17)3-5-13(11)18-12/h2-7,18H,1H3
PDB
MMDB

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Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 30 mins by luciferase-derived luminescence ...


J Med Chem 53: 5054-8 (2010)


Article DOI: 10.1021/jm100476d
BindingDB Entry DOI: 10.7270/Q23X86T4
More data for this
Ligand-Target Pair