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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine 3-monooxygenase' and Ligand = 'BDBM50061913'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kynurenine 3-monooxygenase


(Rattus norvegicus)		BDBM50061913
PNG
(4-Chloro-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benze...)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1csc(NS(=O)(=O)c2ccc(Cl)cc2)n1
Show InChI InChI=1S/C15H10ClN3O4S2/c16-11-4-6-13(7-5-11)25(22,23)18-15-17-14(9-24-15)10-2-1-3-12(8-10)19(20)21/h1-9H,(H,17,18)
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Article
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n/an/a 84n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Kynurenine 3-hydroxylase.

J Med Chem 40: 4378-85 (1998)


Article DOI: 10.1021/jm970467t
BindingDB Entry DOI: 10.7270/Q24B30DT
More data for this
Ligand-Target Pair