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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM50124365'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))
BDBM50124365
PNG
(CHEMBL3623433)
Show SMILES CCCN(C)c1ncc(s1)-c1ccncc1-c1ccccc1Cl
Show InChI InChI=1S/C18H18ClN3S/c1-3-10-22(2)18-21-12-17(23-18)14-8-9-20-11-15(14)13-6-4-5-7-16(13)19/h4-9,11-12H,3,10H2,1-2H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate


J Med Chem 58: 8309-13 (2015)


BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair