Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM50130036'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130036 (CHEMBL3629279) Show SMILES Cc1c[nH]c2ncnc(-c3ccc(NC(=O)Nc4cncnc4)c(F)c3)c12 Show InChI InChI=1S/C18H14FN7O/c1-10-5-22-17-15(10)16(23-9-24-17)11-2-3-14(13(19)4-11)26-18(27)25-12-6-20-8-21-7-12/h2-9H,1H3,(H,22,23,24)(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
					More data for this Ligand-Target Pair