BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Legumain' and Ligand = 'BDBM22131'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Legumain (Ixodes ricinus)	BDBM22131 (aza-peptide Michael acceptor, 7c \| benzyl N-[(1S)-...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	25
Georgia Institute of Technology					Assay Description AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...				J Med Chem 51: 2816-32 (2008) Article DOI: 10.1021/jm701311r BindingDB Entry DOI: 10.7270/Q2KK9937
Georgia Institute of Technology					More data for this Ligand-Target Pair
Legumain (Schistosoma mansoni)	BDBM22131 (aza-peptide Michael acceptor, 7c \| benzyl N-[(1S)-...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	6.8	22
Georgia Institute of Technology					Assay Description AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...				J Med Chem 51: 2816-32 (2008) Article DOI: 10.1021/jm701311r BindingDB Entry DOI: 10.7270/Q2KK9937
Georgia Institute of Technology					More data for this Ligand-Target Pair