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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lethal factor' and Ligand = 'BDBM12006'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lethal factor


(Bacillus anthracis)		BDBM12006
PNG
((1S,2R,3R,4S,5R)-5-amino-2-{[(2R,3R,4R,5S,6R)-3-am...)
Show SMILES [#7]-[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](/[#7])-[#7])-[#6@@H](-[#8]-[#6@H]-2-[#8]-[#6@H](-[#6]\[#7]=[#6](\[#7])-[#7])-[#6@@H](-[#8])-[#6@H](-[#8])-[#6@H]-2-[#7])-[#6@H](-[#8])-[#6@H]-1-[#8] |r|
Show InChI InChI=1S/C14H30N8O6/c15-3-1-4(22-14(19)20)11(10(26)7(3)23)28-12-6(16)9(25)8(24)5(27-12)2-21-13(17)18/h3-12,23-26H,1-2,15-16H2,(H4,17,18,21)(H4,19,20,22)/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 8.80E+3 -28.6n/an/an/an/an/a7.422



Hawaii Biotech Inc.



Assay Description
The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...

Bioorg Med Chem Lett 16: 5183-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.005
BindingDB Entry DOI: 10.7270/Q2VQ30WD
More data for this
Ligand-Target Pair