Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM127887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM127887 (US8791130, 17) Show SMILES CNc1nc(Nc2ccc(cc2OC)-c2cnnn2C)ncc1C(F)(F)F Show InChI InChI=1S/C16H16F3N7O/c1-20-14-10(16(17,18)19)7-21-15(24-14)23-11-5-4-9(6-13(11)27-3)12-8-22-25-26(12)2/h4-8H,1-3H3,(H2,20,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8791130 (2014) BindingDB Entry DOI: 10.7270/Q2K9367R
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