Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM182719'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM182719 (US9145402, 26) Show SMILES CNc1nc(Nc2ccc(cc2OC)S(=O)(=O)N2CCOCC2)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N5O4S/c1-21-15-12(17(18,19)20)10-22-16(24-15)23-13-4-3-11(9-14(13)28-2)30(26,27)25-5-7-29-8-6-25/h3-4,9-10H,5-8H2,1-2H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US9145402 (2015) BindingDB Entry DOI: 10.7270/Q2J67FQ3
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