Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM196725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM196725 (US9212173, 3) Show SMILES Cc1c(Nc2ncc(C#N)c(NC3CC3)n2)cnn1C1CCOCC1 Show InChI InChI=1S/C17H21N7O/c1-11-15(10-20-24(11)14-4-6-25-7-5-14)22-17-19-9-12(8-18)16(23-17)21-13-2-3-13/h9-10,13-14H,2-7H2,1H3,(H2,19,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...				US Patent US9212173 (2015) BindingDB Entry DOI: 10.7270/Q2222SKT
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